POSITION RESPONSIBILITIES Key responsibilities of the role may include, but are not limited to: Serves as the medical monitor for clinical trials and assists in resolving major issues that may affect their assigned studies. Partners with the Clinical Scientist, Data Manager, Pharmacovigilance Scientist, and other members of the study team to conduct the clinical studies, including study design, operational feasibility assessment, and site selection. Provides expert opinion and review for creation of key study documents, including clinical study protocols, safety and medical monitoring plans, charters, and informed consent forms. Interacts closely with Regulatory Affairs to contribute or review clinically relevant components of investigator brochures, briefing books, and other regulatory documents and communications. Working with other members of the clinical study team, conducts investigator meetings, leads site initiation visits, and maintains relationships with clinical trial investigators. Works with internal discovery and translational scientists, technical operations/manufacturing teams, regulatory affairs, safety and pharmacovigilance, and external consultants or CROs in a cross-functional manner. Working closely with the Clinical Research Scientist and other members of the clinical study team (data management, biostatistics, and others), oversees and supports the gathering, analyzing, reviewing, interpreting, and reporting of clinical safety and efficacy data. Supports publication and external communication strategy, acting as owner of clinical data, collaborating in the creation of meeting abstracts, presentations, and publications, and presenting at investigator meetings and scientific conferences as required. CANDIDATE QUALIFICATIONS Required: MD, DO, or equivalent medical degree with experience in patient care at the graduate medical level and beyond. Board certification or substantial clinical experience in hematology, medical oncology, hematology-oncology. At least 3-5 years of experience in clinical investigation in a pharmaceutical or biotechnology company, or equivalent academic clinical trial leadership experience. The Senior Medical Director level typically requires broader independent program leadership experience. Experience in oncology drug development, clinical trial design, medical monitoring, and interpretation of safety and efficacy data. Working knowledge of Good Clinical Practice, clinical trial conduct, and regulatory expectations for oncology development. Demonstrated ability to make independent, timely, and appropriate decisions in a fast-paced biotechnology environment. Excellent interpersonal, verbal, and written communication skills, with the ability to effectively collaborate with cross-functional teams and external stakeholders. Strongly preferred: Direct experience in AML, myeloid malignancies, or leukemia drug development. Experience with T-cell engager, bispecific antibody, cellular therapy, or other immune effector therapies, including CRS/ICANS risk management. LOCATION This position may be remote (in the US), depending on candidate experience and business needs - with occasional travel, or hybrid/based at our corporate offices in Cambridge, MA.  COMPENSATION The salary range for this role is $300,000 - $390,000. The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. We may ultimately pay more or less than the posted range, and the range may be modified in the future. Actual base salary pay for the role may vary within the range based on several factors including, but not limited to, geographic location, candidate experience, skills, relevant education/qualifications, competencies, external market, internal equity, business needs and/or other job-related factors permitted by law.   Additional compensation/benefits include annual bonus opportunity (25% of salary), annual equity awards, medical, dental, vision, life and disability insurance, 401(K) plan with employer match, stock options, employee stock purchase plan, flexible non-accrual paid time off, paid holidays, end-of-year shut down, cell phone reimbursement, tuition reimbursement, paid parental leave.