At CoMind, we are developing a non-invasive neuromonitoring technology that will result in a new era of clinical brain monitoring. In joining us, you will be helping to create cutting-edge technologies that will improve how we diagnose and treat brain disorders, ultimately improving and saving the lives of patients across the world. THE ROLE: The Data Science team at CoMind develops the algorithms and machine learning systems that transform raw optical interference signals from CoMind One into continuous, clinically meaningful measurements of cerebral blood flow, intracranial pressure, and autoregulation. Working at the frontier of photonics, physiology, and applied ML, the team's work directly determines what CoMind One can measure, how accurately, and under what clinical conditions. As Principal Data Scientist, you will be the technical authority for CoMind's data science function, setting methodological direction for signal extraction and ML modelling, personally driving the most complex and highest-impact problems, and providing expert guidance across the team. This is a senior individual contributor role: you will not manage people directly, but your technical leadership will shape how the entire team approaches its most challenging problems. You will work closely with R&D, Clinical, and Software Engineering. At CoMind, all team members work at least 4 days per week from our new Kings Cross offices, plus a flexible work-from-home day. RESPONSIBILITIES: * Own the technical direction for signal processing and ML model development on CoMind One, defining approaches, architectures, and evaluation frameworks that set the standard for the team * Lead the development and validation of the most complex data science components, from novel algorithm design through to evidence generation for regulatory submissions * Act as the primary technical reviewer and expert resource across the data science team, setting the bar for methodological rigour, reproducibility, and scientific integrity * Drive the design and execution of data collection and labelling strategies with Clinical teams, including ground truth definition, dataset governance, and performance benchmarking * Contribute to CoMind's IP and publication strategy, authoring and reviewing technical papers, patent applications, and regulatory documents * Represent the data science function in cross-functional technical forums, architecture reviews, and external scientific and clinical engagements * Identify and introduce new methods, tools, and approaches that advance CoMind's signal extraction and ML capabilities * AI is fundamental to our culture. It's not just a tool, but a core part of how we work, collaborate, and innovate. We expect all team members to embrace AI in their daily work and continuously find new ways to use it effectively. SKILLS & EXPERIENCE: * 15+ years of experience in data science, ML, or applied research, with a strong track record of independent technical leadership on complex, ambiguous problems * Deep expertise in time-series signal processing and physiological or biomedical ML, including hands-on experience developing and validating models on noisy, real-world physiological data * Demonstrated ability to take algorithmic work from research through to production-quality, validated implementation * Experience in a regulated industry (medical devices, diagnostics, pharma, or similar), with familiarity with algorithm validation and documentation requirements for software as a medical device * Strong record of scientific output: publications, patents, or equivalent evidence of original technical contribution and domain authority Nice to Have * Background in neuroscience, neuromonitoring, neurophotonics, and/or cerebrovascular physiology * Experience with optical signal processing - e.g. LiDAR, pulse oximetry, NIRS, laser doppler flowmetry, or related technologies * Familiarity with FDA regulatory pathways for AI/ML-based medical devices BENEFITS: * Company equity plan so all employees share in the success of the company * Salary-sacrifice pension scheme * Private medical, dental and vision insurance (medical history disregarded) * Group life assurance at 4x annual income * Comprehensive mental health support, including unlimited access to 1:1 sessions with trained professionals * Unlimited holiday allowance (+ bank holidays) and one week of remote working per quarter * Lunch voucher (£10) every day for JustEat and free dinner on those days where you need to work later * Twice weekly deliveries of fresh fruit and an extensive selection of snacks and drinks * YuLife subscription, allowing you to turn your daily steps and meditation into discounts at a range of stores * Access to Udemy for upskilling and professional development.