Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS). Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply. The Opportunity The Accounts Payable (AP) Specialist is primarily responsible for the entry and auditing of invoices and credits in NetSuite, the reconciliation of vendor statements and the management of the AP and Concur mailboxes. The ideal candidate will maintain a consistent turnaround on invoice processing, expense auditing, vendor and employee inquiries, and Concur-related activities while ensuring compliance with company policies and procedures in a fast-paced environment. We will be hiring the Accounts Payable Specialist role in September 2026 Responsibilities * Assist with the management of the AP and Concur mailboxes, responding to vendor and employee inquiries within 48 hours. * Process invoices and payment requests in NetSuite for assigned accounts in compliance with the Amylyx Purchase Order and Expenditure Policy, including verifying receipt of goods and services, resolving discrepancies, recording applicable taxes, and following up on outstanding draft invoices. * Audit employee travel and entertainment expenses (T&E) in Concur for compliance with the Amylyx T&E policy, communicate audit findings, and identify, track, and follow up on personal spend related to corporate cards. * Complete monthly reconciliations and monitoring of assigned critical vendor accounts, including downloading and processing invoices as needed. * Reconcile vendor statements for assigned accounts and work directly with vendors to resolve discrepancies and obtain missing documentation. * Support the administration of the Concur platform, including user maintenance, reporting, approval workflow updates, corporate card administration, and employee support. * Assist with NetSuite and Concur testing, system enhancements, annual audit requests, 1099 review activities, and continuous process improvement initiatives related to invoice and payment processing. * Comply with all Amylyx policies and procedures and provide recommendations to improve AP and T&E processes. Required Qualifications * Bachelor's degree in Accounting, Finance, Bus Admin * 1–3 years of Accounts Payable experience * Demonstrated knowledge of AP including T&E principles and best practices. * Ability to work in an automated ERP system and expense reporting systems. * Excellent problem-solving skills, ability to research issues related to the AP cycle and T&E auditing. * Strong, accurate data entry skills, high attention to detail. * Excellent communication skills. Able to maintain a high level of customer service, does what is necessary to ensure customer satisfaction, manages service failures and prioritizes customer needs. * Exceptional organizational skills, ability to prioritize workload and manage multiple priorities. * Able to work independently with an appropriate level of supervision. * Willingness to work collaboratively with all team members and provide support as needed. * MS Office experience required. Preferred Requirements * Oracle NetSuite and Concur experience a plus. * Advanced Excel skills, including pivot tables, lookups, and reporting. * Experience in biotech/pharma/life sciences Work Location and Conditions * At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan and Tennessee. * You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested. * You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location. Compensation The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity. Estimated Pay Range $65,000—$73,000 USD To stay connected with us, follow Amylyx Pharmaceuticals on LinkedIn. To return to our website please click here. Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

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