Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed. The Opportunity Praxis is scaling for commercial launch. We’re looking for an Enterprise Applications Development Lead to build, integrate, and support the systems that help our teams operate reliably as we grow. You will spend the majority of your time on hands-on work: configuring SaaS applications, developing SQL and data integrations, automating workflows, investigating issues, and delivering tested improvements. Initial priorities include enterprise application support, ERP and CRM integrations, and dependable access to commercial data. You will own technical delivery and day-to-day reliability for assigned applications, working with Commercial, Finance, the People Team, and IT. This is an individual contributor role with leadership through technical expertise and execution. You will work within the priorities and architecture established with IT leadership, partnering with application engineering, data engineering, security, and validation colleagues. Primary Responsibilities * Build, configure, administer, and support assigned enterprise applications and workflows across the SaaS environment, including systems such as SAP, Salesforce/Veeva, Greenhouse, and Ketch. * Develop and maintain SQL queries, data models, integrations, and automated workflows using APIs, middleware, file exchanges, and scripting. Implement reconciliation, error handling, monitoring, and recovery procedures. * Support SAP and CRM implementations and enhancements through data mapping, migration, integration development, testing, and production troubleshooting with business owners and implementation partners. * Partner with Data & Analytics to connect application data to commercial reporting and the commercial data foundation. Maintain tested SQL queries and documented access procedures so critical monitoring can continue when AI interfaces are unavailable. * Translate business needs into clear requirements, practical technical designs, and deliverable work items. Configure standard platform capabilities where appropriate and develop custom solutions when justified. * Own issues through resolution: diagnose failures, coordinate vendor support, communicate business impact, and address recurring causes. Maintain runbooks and cross-train colleagues to provide dependable backup coverage. * Coordinate technical work with vendors and internal teams. Maintain application documentation, support contacts, and license usage information; recommend simplification and flag renewal or support risks to IT leadership. * Use version control, peer review, repeatable deployment, and appropriate testing. Partner with Security and IT Validation on access controls, change documentation, and validation evidence for regulated workflows. Qualifications * 8+ years of relevant experience in enterprise applications, ERP/CRM systems, database development, or data engineering, with recent hands-on delivery and production support responsibilities. * Strong SQL development skills, including relational data modeling, troubleshooting, data quality, and performance tuning; practical scripting experience with Python or a comparable language. * Experience configuring or supporting enterprise SaaS platforms and integrating ERP or CRM systems. Relevant experience may include Microsoft Dynamics 365, SAP, Salesforce, or comparable platforms. * Hands-on experience building and maintaining ETL/ELT processes and integrations using APIs, middleware, or file-based exchanges, with attention to reliability and recoverability. * Ability to work directly with business users, clarify requirements, test solutions, and carry changes through deployment and ongoing support. * Experience with Git or comparable version control, issue tracking, technical documentation, and disciplined release practices. * The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions. Annualized Base Salary $130,000—$150,000 USD Compensation & Benefits At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive.  This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future?  We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP.  We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns.  Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring.  We aim high, collaborate hard, and produce results.  Let’s achieve the impossible together! Company Overview Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members. Diversity, Equity & Inclusion Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws. Attention: Job Scam Alert Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to [email protected]. Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.

Enterprise Applications Development Lead

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