Mirrai Careers

Research Scientist In Vitro Pharmacology

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Cambridge, MA Full-time Posted 2w ago
KEY RESPONSIBILITIES * Design, optimize, and run functional assays in appropriate cellular liver disease models, selecting systems that capture the relevant disease biology and therapeutic mechanism. * Evaluate ADAR-mediated RNA editing and siRNA candidates and characterize dose response, durability, cellular phenotype, and disease-relevant biomarkers using orthogonal readouts. * Develop and apply key end points for functional assays (viability assays, ELISA or MSD, and Western blot or Jess) and high-content imaging workflows for phenotyping and quantitative analysis. * Interpret results…

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